Description
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XANAX 0.25 (Xanax 0.25 mg) Generic Name: alprazolam , Pill with imprint XANAX 0.25 is White, Elliptical / Oval, and has been identified as Xanax 0.25 mg. It is supplied by Pfizer U.S. Pharmaceuticals Group.
In several doses.
Anxiety: > 18 years: at first 0.75–1.5 mg / day, then 0.5–4 mg / day; elderly or debilitated patients: at first 0.5–0.75 mg / day, then ev. gradually increase.
Panic disorder: > 18 years: at the start 0.5–1.5 mg / day, then ev. increase the daily dose by max. 1 mg every 3–4 days. at 4 – max. 6 mg / day.
Discontinuation of treatment: if treatment duration> 1 week, reduce the daily dose in steps of max. 0.5 mg every 3 days.
Delayed tablets
In a single dose in the morning or in 2 divided doses.
Anxiety: > 18 years: at the beginning 1 mg / day, then 0.5–4 mg / day; elderly or debilitated patients: at the beginning 0.5–1 mg / day, then ev. gradually increase.
Panic disorder:> 18 years: at the start 0.5–1 mg / day, then ev. increase to 4 – max. 6 mg / day.
Discontinuation of treatment: if treatment duration> 1 week, reduce the daily dose in steps of max. 0.5 mg every 3 days.
DESCRIPTION
Alprazolam Tablets, USP contain alprazolam which is a triazolo analog of the 1,4 benzodiazepine class of central nervous system active compounds.
The chemical name of alprazolam is 8-Chloro-1-methyl-6-phenyl-4 H– s-triazolo[4,3-α][1,4] benzodiazepine.
Alprazolam is a white crystalline powder, which is soluble in methanol or ethanol but which has no appreciable solubility in water at physiological pH.
Each alprazolam tablet, for oral administration, contains 0.25, 0.5, 1, or 2 mg of alprazolam.
Alprazolam tablets, 2 mg, are multi-scored and may be divided.
Inactive ingredients: Colloidal silicon dioxide, docusate sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium benzoate, and sodium starch glycolate. In addition, the 0.5 mg tablet contains FD&C Yellow No. 6 Aluminum Lake and the 1 mg tablet contains FD&C Blue No. 1 Aluminum Lake.
Xanax Side effects
In addition to its desired action, this medication may cause some side effects, notably:
- it may cause drowsiness or dizziness — use caution if driving;
- it may cause unusual tiredness;
- it may make your skin more sensitive to UV rays (e.g., sunlight, tanning lamps) – avoid exposure to UV rays as much as possible and protect yourself when out in the sun;
- it may affect your mood;
- it may affect your memory;
- it may affect your appetite.
Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.
Status Epilepticus and its Treatment
The medical event voluntary reporting system shows that withdrawal seizures have been reported in association with the discontinuation of alprazolam tablets. In most cases, only a single seizure was reported; however, multiple seizures and status epilepticus were reported as well.
Interdose Symptoms
Early morning anxiety and emergence of anxiety symptoms between doses of alprazolam tablets have been reported in patients with panic disorder taking prescribed maintenance doses of alprazolam tablets. These symptoms may reflect the development of tolerance or a time interval between doses which is longer than the duration of clinical action of the administered dose. In either case, it is presumed that the prescribed dose is not sufficient to maintain plasma levels above those needed to prevent relapse, rebound or withdrawal symptoms over the entire course of the interdosing interval. In these situations, it is recommended that the same total daily dose be given divided as more frequent administrations (see DOSAGE AND ADMINISTRATION).
Risk of Dose Reduction
Withdrawal reactions may occur when dosage reduction occurs for any reason. This includes purposeful tapering, but also inadvertent reduction of dose (e.g., the patient forgets, the patient is admitted to a hospital). Therefore, the dosage of alprazolam tablets should be reduced or discontinued gradually (see DOSAGE AND ADMINISTRATION).
CNS Depression and Impaired Performance
Because of its CNS depressant effects, patients receiving alprazolam tablets should be cautioned against engaging in hazardous occupations or activities requiring complete mental alertness such as operating machinery or driving a motor vehicle. For the same reason, patients should be cautioned about the simultaneous ingestion of alcohol and other CNS depressant drugs during treatment with alprazolam tablets.
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